Medicines Information for health professionals in Ireland

To see the importance of having an accurate medicines reference available to health professionals in Ireland, consider the level of fluctuation in the availability of medicines. This depends on new arrivals as well as existing medicines that have recently been withdrawn or discontinued. Either way, the health professionals needs clear information about alternatives.

Below is a list of medicines discontinued / withdrawn from the Irish healthcare setting. 

By referring to the latest edition (IMF 37, September 2025) health professionals can always keep track and ensure their medication decisions always reflect safer, more effective and evidence-based information.

This list will be updated when IMF 38 is published, March 2026

No Longer Available

Discontinued before publication of IMF 37, September 2025:

  • Adcortyl Parenteral 10mg/mL
  • Alendronic Acid Accord Once Weekly
  • Amoclav (250/125mg strength only)
  • Aprovel (range)
  • Azacitidine Rowex Parenteral 25mg/mL
  • Betagan UDV 5mg/mL Eye Drops
  • Betnovate RD Cream
  • Bortezomib Mylan Parenteral 3.5mg
  • Buscopan Rx (still available as OTC)
  • Combigan Eye Drops
  • COSOPT Eye Drops (only preservative-free UDV)
  • Creon (40000 strength only)
  • Darunavir Rowex 800mg
  • Diabrezide 80mg
  • Diazepam (Accord) 2mg, 10mg
  • Diclac Parenteral 25mg/mL
  • Differin 0.1% (Cream formulation only)
  • Diprobase Cream, Ointment
  • Donecept 5mg, 10mg
  • Dorzolamide/Timolol (Accord) Eye Drops
  • Eczibet Cream
  • Enerzair Breezhaler
  • Etrivex Shampoo 500mcg/g
  • FEIBA (50 U/mL strength only)
  • FML 0.1% Eye Drops Suspension
  • Fucidin 250mg tablets
  • Imigran Ftab 100mg (2-pack only)
  • Irbesartan Accord (entire range)
  • Ivabradine Accord 5mg, 7.5mg
  • Lamictal Dispersible Tablets (5mg-strength only)
  • Lanoxin Parenteral 500mcg/2mL
  • Lanzol (15mg strength only)
  • Losartan Rowa (100mg strength only)
  • Motilium Oral Suspension
  • Nicochew Mint Gum 2mg, 4mg
  • Nizoral Cream 2%
  • Normacol 62% Granules
  • Olmesartan (Gerard) (entire range)
  • OxyContin (80mg strength only)
  • Pantoflux 20mg, 40mg
  • Phyllocontin Continus 225mg
  • Pramipexole Accord 0.18mg
  • Pred Mild 0.12% Eye Drops
  • Primacine Susp 125mg, 250mg
  • Raloxifene (Accord) 60mg
  • Ramipril (Accord) 2.5mg, 5mg, 10mg
  • Relestat Eye Drops 0.5mg/mL
  • Reminyl (entire range)
  • Reminyl Oral Soln
  • Rolyprexa (2.5mg, 15mg strengths only)
  • Saflutan Eye Drops (Multidose bottle)
  • Salofalk (tablets 250mg only)
  • Seroxat (10mg, 30mg strengths only)
  • Spasmonal (60mg strength only)
  • Stesolid Rectal Tubes (entire range)
  • Stieprox 15mg/g Shampoo
  • Stilnoct 5mg (14-pack only)
  • Synagis Parenteral 100mg/mL
  • Targin Prolonged Release (60mg/30mg strength only)
  • Tavanic 500mg
  • Tavanic Parenteral 5mg/mL
  • Tendrotil SR 2mg, 4mg
  • Tenkasi Parenteral (400mg strength replaces with 1200mg strength)
  • Timoptol Eye Drops 0.25%, 0.5%
  • Tradol Injection 100mg/2mL
  • Tritace (1.25mg strength only)
  • Uniphyllin Continus tablets (200mg, 300mg only)
  • Viscolex Syrup 250mg/5mL
  • VisuXL Eye Drops (rest of range remains)
  • VisuXL Gel (5mL presentation only)

Discontinued before publication of IMF 36, March 2025:

  • Apixaban (Accord) (range)
  • Aspirin (Clonmel) 75mg
  • Belkyra Parenteral 10mg/mL
  • Brinzolamide (Accord) Eye Drops
  • Carbimazole (Essential) Tablets (range)
  • Centrax 10mg
  • Cinacalcet Rowex (range)
  • Comirnaty Original COVID-19 Vaccine
  • Comirnaty Original/Omicron BA.1 COVID-19 Vaccine
  • Comirnaty Original/Omicron BA.4-5 COVID-19 Vaccine
  • Eligard Parenteral (7.5mg strength only)
  • FEIBA Parenteral (25 IU/mL strength only)
  • Femara 2.5mg
  • Fingolimod Krka 0.5mg
  • Flamazine Cream
  • Imatinib (Pinewood) (entire range)
  • JCOVDEN COVID-19 Vaccine
  • Latanoprost (Accord) Eye Drops 50mcg/mL
  • Levemir Innolet 100 units/mL
  • Losamel 20mg
  • Nemdatine 10mg
  • Nuvaxovid COVID-19 Vaccine
  • OCALIVA 5mg, 10mg
  • Oruvail 200mg
  • Repaglinide (Accord) (range)
  • Simvastatin (Accord) (range)
  • Spikevax Original/Omicron BA.4-5 COVID-19 Vaccine
  • Spikevax Original COVID-19 Vaccine
  • Spikevax Original/Omicron BA.1 COVID-19 Vaccine
  • Terbasil 250mg

Discontinued before publication of IMF 35, September 2024:

  • Hyrimoz Parenteral 40mg
  • Agomelatine Accord 25mg
  • Bonefurbit 150mg
  • Celecoxib (Key) 100mg, 200mg
  • Diflazole (range)
  • Entyvio Parenteral 108mg (PFS only)
  • Fluenz Tetra Nasal Vaccine (flu vaccine)
  • Fungasil 1% Cream
  • Giotrif (50mg strength only)
  • Irprestan (range)
  • Isomonit Retard 60mg
  • Komboglyze (entire range)
  • Memantine LEK 10mg
  • MST Continus  (60mg strength only)
  • Onglyza (2.5mg strength only)
  • Oxis Turbohaler (range)
  • Prosentio 100mg
  • Prozac 20mg (parallel import)
  • Pulmicort Turbohaler 100mcg (200-dose)
  • Purinol (range)
  • Temodal Capsules (entire range)
  • Vaxzevria COVID-19 Vaccine
  • Zaltrap Parenteral 25mg/mL
  • Zolpidem (Key) 5mg, 10mg

Discontinued before publication of IMF 34, March 2024:

  • Acetylcysteine Essential 600mg
  • Acidex Suspension (entire range)
  • Aldara 5% Sachets
  • Amlodipine/Valsartan/HCTZ (Rowex) (entire range)
  • Aprovel (75mg strength only)
  • Azithromycin (Accord) 250mg
  • Benetor (entire range)
  • Benetor Plus (entire range)
  • Betnovate-C Cream
  • Blopress (entire range)
  • Blopress Plus (entire range)
  • Cinacalcet Accord (range)
  • Cinacalcet Rowex (30mg strength only)
  • Colifoam 10% Rectal Foam
  • Dalmpam (entire range)
  • Dexketoprofen Rowex 25mg
  • Dorzolaminde Accord Eye Drops
  • Doxacar Prolonged/R 4mg
  • Efavirenz Rowex 600mg
  • Emend (2-day treatment pack only)
  • Ezetimibe/Simvastatin (Mylan) (entire range)
  • Feldene Topical Gel
  • Flagyl 1g Suppositories
  • Flagyl tabs (200mg strength only)
  • Foradil Aerolizer 12mcg
  • Galfer FA
  • Gyno-Daktarin (entire range)
  • Ikorel (range)
  • Kapake (entire range)
  • Klariger 500mg
  • Lipertance Tablets (range)
  • Lipocomb Capsules (range)
  • Mirvaso Gel
  • Nutilis Powder (300g pack only)
  • Ondansetron (Rowex) Parenteral
  • Ondansetron (Rowex) Tablets (entire range)
  • Pantoprazole Mylan (entire range)
  • Pemetrexed Rowex 25mg/mL (all presentations)
  • Pradaxa 150mg (10-pack only)
  • Pravastatin (Accord) (entire range)
  • Pravastatin Mylan (entire range)
  • Psoriderm Cream
  • Rabeprazole (Accord) (range)
  • Rasagiline Mylan 1mg
  • Razole 20mg
  • Rivastigmine Sandoz Caps (entire range)
  • Rosuva Tablets (entire range)
  • Rozex Cream/Gel
  • Selincro 18mg (14-pack only)
  • Sevredol (50mg strength only)
  • Sibelium 5mg
  • Sildenafil Mylan (entire range)
  • Skudexa (granule presentation only)
  • Solifenacin (Myland) (10mg strength only)
  • Steglatro (entire range)
  • Steglujan (entire range)
  • Tavanic (250mg strength only)
  • Telmisartan Mylan (entire range)
  • Telmisartan/Hydrochlorothiazide Rowa (80/25 strength only)
  • Zinnat (125mg tablet only)
  • Zofran Parenteral
  • Zykadia 150mg

Updated: 18 February 2026